[color=color_url - Researchers analyzed randomized trials that had been published between January 2004 and May 2014, choosing 24 involving mixed populations of patients who were treated with PDE5i or a placebo. PDE5i was given to men who had cardiovascular disorders, but who did not necessarily suffer from sexual impotence, according to Isidori. The study found that the inhibitor prevented the heart from changing shape in patients suffering from left ventricular hypertrophy, a condition that causes thickening and enlargement of the heart muscle. The drug also improved functioning of the heart in patients with a variety of cardiac conditions, with no effect on blood pressure. In fact, researchers found that the drug improved efficiency when the heart pumped http://escortparis.biz - escortparis.biz [color=color_url - blood into vessels, along with relaxation between beats. “Very few drugs used in cardiology can actually affect these parameters. For this reason their implications in the treatment and prevention of heart failure are huge.” “But in all studies, to the best of my knowledge, it’s not shown any increase in cardiac events in patients who take these drugs,” he said. Past studies have suggested Viagra and other PDE5 inhibitors may have benefits for heart failure by decreasing pulmonary artery resistance and providing cardio-protective effects in settings with low blood flow, according to Kociol. “They also improve exercise tolerance in patients with heart failure,” he said. The drug may even reduce the size of a heart attack. But Kociol said scientists have to “temper” their enthusiasm as more studies are necessary. “As interesting as this paper is, there have been conflicting results,” he said. “If there is a silver bullet, it remains to be seen.” Kociol added that researchers also need to “pay more attention” differences between men and women and between racial groups. Some earlier research suggests that drugs like Viagra might interact differently with estrogen, which is known to have naturally protective properties for the heart. However, Isidori notes that because these studies were conducted exclusively on men, the next step should be a larger trial on women.
Поделиться ВКонтакте
